Reliable COVID-19 Vectors
Safe COVID-19 vectors with variant spike proteins to study viral entry and test COVID-19 antivirals
Enabling Safe and Scalable SARS-CoV-2 Research Outside BSL-3
Since the emergence of SARS-CoV-2 in late 2019, the global scientific community has raced to understand, track, and counter the virus through vaccines, therapeutics, and molecular research. However, working with live SARS-CoV-2 requires BSL-3 containment, which remains a significant barrier for many labs. Tailored Genes bridges that gap by offering a suite of BSL-2-compatible lentiviral vector tools for studying SARS-CoV-2 entry, spike protein expression, and antiviral screening — including tools for major variants of concern.
What We Offer
SARS-CoV-2 Pseudotyped Lentivirus Vectors
Tailored Genes has developed high-titer lentiviral vectors pseudotyped with the spike protein from the original SARS-CoV-2 strain, allowing researchers to safely study viral entry mechanisms and perform antiviral neutralization assays under BSL-2 conditions.
- Available with eGFP or luciferase reporters for visual or luminescence-based quantification
- High purity and titer (10⁸ IU/mL) for efficient cell transduction
- Ideal for ACE2-expressing target cells
SARS-CoV-2 Variant Vectors
To support variant-specific research, we offer SARS-CoV-2 spike protein pseudotyped lentivirus vectors for the major global variants:
- Alpha
- Beta
- Delta
- Gamma
LVV CoV2 Spike Expression Vector
We’ve also engineered a lentiviral vector expressing the SARS-CoV-2 spike gene for direct transduction of target cells and vector expressing ACE-2 receptor protein for COVID-19.
- Enables testing of antiviral or vaccine candidates against variant strains
- Suitable for studying host response, cell viability, and spike-driven processes
- High-titer and high-purity, available with eGFP or luciferase reporters
- Available upon request
Why Use Tailored Genes’ SARS-CoV-2 Tools?
Safe for BSL-2 Labs
No need for BSL-3 containment to study viral entry or test antiviral compounds
Fast, Scalable Testing
Easily adaptable for high-throughput antiviral and vaccine screening
Variant Coverage
Study how emerging spike mutations affect drug and antibody efficacy
High-Performance Vectors
Consistently high titers and purity ensure reliable transduction and reproducibility
Expert Support
Access consultation for experimental design, vector use, and result interpretation
Accelerate Your COVID-19 Research?
Contact Tailored Genes to request a quote, place an order, or discuss how our lentiviral SARS-CoV-2 vectors can support your vaccine, drug, or basic research programs.
Our Solutions
Explore More Manufacturing Solutions
Expertly crafted virus vectors and cell line solutions—powering research from bench to breakthrough.
Adeno-Associated Virus (AAV)
High titer (10¹³ and 10¹⁴ GC/mL) and ultra pure AAV vectors.
Stable Cell Lines
Overexpress or repress gene expression in the cell line of your choice.
Lentivirus Vectors
High titer (10⁸–10⁹ IU/mL) and high purity LV vectors.
