Adeno-Associated Virus(AAV) Services
AAV vectors tailored to your research, backed by over 30+ years of expertise.
Harnessing AAV for Safe and Targeted Gene Delivery
Adeno-Associated Virus (AAV) is a powerful tool for gene therapy, capable of delivering DNA to target cells with high precision and efficiency. AAV is a non-enveloped virus that has become a gold standard for gene delivery due to its safety and versatility in targeting different cell types.
Key Advantages of AAV
AAV is a preferred gene therapy vector due to its precision, low immune response, and ability to target diverse cell types safely and effectively.
Non-Pathogenic
AAV does not cause any known human disease, making it a safe option for gene delivery.
Low Immunogenicity
Elicits only a mild immune response, reducing the risk of adverse reactions.
Broad Targeting Capability
Can target both dividing and non-dividing cells.
Tissue-Specific Targeting
Different serotypes allow for targeting specific tissues with precision.
AAV Services
Our AAV Services
We specialize in providing high-quality AAV vectors customized to meet your research and therapeutic needs. Our AAV production includes:
01.
High Purity, High Titer Vectors
Available in serotypes 1, 2, 5, 9, and PHP.eb. Other serotypes to follow.
02.
Custom Plasmid Design
Tailored to optimize transgene expression
03.
Vector Production & Purification
Delivered at industry-leading purity & titer levels
04.
Comprehensive Quality Control
Including full/empty capsid ratio and purity testing
05.
Gene-Specific
Titers
Ensuring accurate delivery and expression
01. Personalized Support for Every Project
Not sure which AAV vector is right for your project? Our team of experts provides one-on-one consultation to help you:
- Design the optimal plasmid configuration for your gene of interest
- Select the best AAV serotype for your target tissue
- Determine the right amount of vector for your application
Our guidance ensures you achieve the highest levels of efficiency and accuracy in your research.
02. Quality Control & Characterization
We take quality seriously. Every batch of AAV vectors undergoes rigorous testing to ensure consistent performance:
- Full/empty capsid ratio
- Purity testing
- Gene-specific titer analysis
FAQs
Frequently Asked Questions
Got questions? We’ve got answers. Browse through the most common questions to learn more about how we work, what we offer, and how we can help.
AAV vectors should be stored immediately at -80°C. All our vectors have shelf-life of one year without loss in titer.
We recommend not to freeze-thaw your viral vector preparations multiple times. If you plan to use the virus for multiple experiments, thaw the viral preparation on ice, remove the desired volume for use in experiment, aliquot the remaining viral vector preparation into smaller aliquots, and snap-freeze aliquots in dry ice before storing at -80°C.
The maximum gene capacity between the two ITRs of an AAV vector is 4.5kb.
We determined the number of viral genomes/mL of purified prep. This is determined by Absolute Q Digital PCR and/or by UV/vis concentration and Dynamic light scattering UV/Vis (Stunner machine).
AAV vectors
PBS pH 7.4 and 0.001% pluronic acid F68
Why Choose Us for AAV Production?
At Tailored Genes, we’re committed to delivering high-quality AAV vectors with speed, reliability, and personalized support. All of our vectors are manufactured in North America, ensuring compliance with stringent quality standards. Whether you need small-scale production in just one week or large-scale batches in two to three weeks, our streamlined process delivers results fast. We also back every order with a satisfaction guarantee—if something isn’t right, we’ll work closely with you to make it right.
- North American Manufacturing – All vectors are produced in North America, ensuring strict quality standards.
- Fast Turnaround Times – 1 week for small-scale, 2–3 weeks for large-scale production.
- Satisfaction Guarantee – We follow up after delivery to ensure the vectors meet your expectations. If issues arise, we’ll work with you to resolve them.
Our Solutions
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